用纤维支气管镜检查236例肺部感染者的病原学分析

THE BACTERIOLOGY OF RESPIRATORY INFECTIONS INVESTIGATED BY DOUBLE-PLUGGED CATHETER BRUSH SYSTEM VIA FIBEROPTIC BRONCHOSCOPE一A PROSPECTIVE STUDY OF 236 CASES

本文报告了２３６例支气管肺部感染者，用纤支镜双塞保护法采样，病原菌培养结果。总阳性率７４．６％。共分离到２２种２９１株病原菌。球茵占１６．７％、肠杆菌科占１１．７％、非发酵菌占３７．１％，厌氧菌占２２．３％、真菌占１２．７％，３９．２％的病例为复合菌感染。还报告了８种带见病原菌对２８种抗生素的敏感试验结果。对近年肺部感染的病原菌谱型变化及复合菌感染等进行了讨论。

The distribution of pathogens from 236 patients with respiratoryinfections was reported.The specimens were obtained by a dotible-pluggedcatheter brush system via fiberoptic bronchosccpe.The isclats ≥103CFU/ml and the isolats≥ 102CFU/ml in polymicrobial infection wereconsldered as pathogens 176 cases were positive culture, while 291 strainsof pathogens were recovered.The rate cf recovery was 74.6%,Thedistribution was as follows:16.7%(cocci),11.7%(enteric grem negati-ve rods), 37.1%(non fermenting gram negative rods),22.3%(anaerobicbacteria),12.7%(Candida).Incidence of polymicrcbial infection was39.2%,The sensitivity of frequent pathogens against 28 antibiotics wasalso reported,New-quinolons and cephems of third-generation wereactive against most pathogons,The result showed that the presentdistribution of pathogens is significantl ydifferent from previous ones.More attention should be paid to polymicrobial infection.