摘要
A new kind of fluorine-containing amphiphiles -- perfluoroalkyl-containing steroidal glycos- ides were synthesized in good yield through perfluoroalkylation by means of sodium dithionite-initiated addition of R_FI to olefinic system. Preliminary study showed that these glycosides could form vesicles in aqueous medium as observed by electron microscopy.
A new kind of fluorine-containing amphiphiles -- perfluoroalkyl-containing steroidal glycos- ides were synthesized in good yield through perfluoroalkylation by means of sodium dithionite-initiated addition of R_FI to olefinic system. Preliminary study showed that these glycosides could form vesicles in aqueous medium as observed by electron microscopy.
基金
This work was pedially sapported by the National Natural Science Foundation of China.