摘要
Treatment of pyroyunaconitine 1 with NBS—1% HCI soln.at room temperature for 12 h.leads to compound 2 having an α,β—unsaturated ketone system in 15% yield.It is easi- ly converted to 3 via an acyloin rearrangement during purification.Structures of 2 and 3 were elucidated by spectral methods.
Treatment of pyroyunaconitine 1 with NBS—1% HCI soln.at room temperature for 12 h.leads to compound 2 having an α,β—unsaturated ketone system in 15% yield.It is easi- ly converted to 3 via an acyloin rearrangement during purification.Structures of 2 and 3 were elucidated by spectral methods.
