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A NEW PROCESS FOR THE EXTRACTION OF PENICILLIN G FROM THE FILTRATE OF FERMENTATION BROTH WITH TBP IN BUTYL ACETATE

A NEW PROCESS FOR THE EXTRACTION OF PENICILLIN G FROM THE FILTRATE OF FERMENTATION BROTH WITH TBP IN BUTYL ACETATE
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摘要 The mixture of neutral phosphorus esters and butyl acetate (BA) can be used, as the extractant for the extraction of penicillin G. The extraction equilibrium pH can be increased to pH3—4 due to the stronger extraction capability of the solvent mixture, instead of pH1.8—2.2 with butyl acetate as solvent. The experimental results indicate that the total recovery of penicillin G can reach 96.6% with the new extraction process, which is 5—6% higher than that obtained with the traditional process using BA as solvent at pH1.8—2.2. The mixture of neutral phosphorus esters and butyl acetate (BA) can be used, as the extractant for the extraction of penicillin G. The extraction equilibrium pH can be increased to pH3—4 due to the stronger extraction capability of the solvent mixture, instead of pH1.8—2.2 with butyl acetate as solvent. The experimental results indicate that the total recovery of penicillin G can reach 96.6% with the new extraction process, which is 5—6% higher than that obtained with the traditional process using BA as solvent at pH1.8—2.2.
出处 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 1992年第1期83-92,共10页 中国化学工程学报(英文版)
关键词 solvent EXTRACTION PENICILLIN G TBP BUTYL ACETATE solvent extraction penicillin G TBP butyl acetate
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