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Experimental study on vasoactive intestinal peptide—like immunoreactivity in plasma and brain in high—velocity missile injuries of extremity

Experimental study on vasoactive intestinal peptide—like immunoreactivity in plasma and brain in high—velocity missile injuries of extremity
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摘要 Experimental high-velocity missile injuries were produced on both hind legs of 15 dogs.It was found that the concentration of vasoactive intestinal peptide-like immunoreactivity(VIP-LI)significantly elevated in both plasma and brain at the early stage after injuries.However,thechanges of VIP-LI concentration in the plasma and brain did not coincide with each other.The re-sults suggest that VIP-LI may participate in the post-traumatic general reaction.The significanceand machanism of the elevation of cerebral VIP-LI level after a severe non-cerebral trauma remainto be clarified. Experimental high-velocity missile injuries were produced on both hind legs of 15 dogs. It was found that the concentration of vasoactive intestinal peptide-like immunoreactivity(VIP-LI) significantly elevated in both plasma and brain at the early stage after injuries.However,the changes of VIP-LI concentration in the plasma and brain did not coincide with each other.The re- sults suggest that VIP-LI may participate in the post-traumatic general reaction.The significance and machanism of the elevation of cerebral VIP-LI level after a severe non-cerebral trauma remain to be clarified.
出处 《Journal of Medical Colleges of PLA(China)》 CAS 1992年第1期36-40,共5页 中国人民解放军军医大学学报(英文版)
关键词 WOUNDS GUNSHOT peptides blood BRAIN CEREBROSPINAL fluid dogs wounds gunshot peptides blood brain cerebrospinal fluid dogs
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