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尿微量蛋白在肾病中的变化及意义 被引量:4

Changes of uric microprotein in nephropathy and its significance
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摘要 目的 探讨尿微量蛋白在肾病中的变化及临床意义。方法 采用速率散射比浊法检测 196例肾病患者尿微量蛋白水平。结果 肾病患者尿微量白蛋白 (MA)、转铁蛋白(TRF)、α1-微球蛋白 (α1-MG) ,免疫球蛋白G(IgG)水平均显著高于对照组 (P <0 .0 1) ,8种原发性、继发性肾病患者尿微量白蛋白水平显著高于对照组 ,尿素氮 (BUN)、肌酐 (Cr)异常的肾病患者 ,其尿微量白蛋白含量与BUN ,Cr呈显著正相关 (P均 <0 .0 5 )。结论 尿微量蛋白与肾脏病变密切相关 。 Objective It is to discuss the changes of uric microprotein in nephropathy and its clinical significance.Methods The levels of uric microprotein in 196 nephropathy patients were measured with speed scatter nephelometer.Results The levels of uric microprotein in nephropathy patients were significantly higher than those in control group (P<0.01). The levels of uric microalbumin in 8 dinds of primary and secondary nephropathy patients were significantly higher than those in control group. The contents of uric microalbumin in the patients whose blood urea nitrogen (BUN) and creatinine (Cr) were abnormal were correlated positively with BUN and Cr (P<0.05).Conclusion There is closely related between the levels of uric microprotein and nephropathy. Uric microalbumin may be used as a nicer index of nephropathy.
出处 《现代中西医结合杂志》 CAS 2004年第13期1698-1699,共2页 Modern Journal of Integrated Traditional Chinese and Western Medicine
关键词 尿微量蛋白 肾病 尿素氮 肌酐 uric microprotein nephropathy blood urea nitrogen creatinine
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参考文献3

  • 1Price CP,Newman DJ,Blirup-Jensen S,et al. First international reference preparation for individual proteins in urine[J]. Clin Biochem,1998,31(6):467-474
  • 2Parikh CR,Gyamlani GG,Carvounis CP,et al. Screening for microalbuminuria simplified by urine specific gravity[J]. Am J Nephrol,2002,22(4):315-319
  • 3Unuigbe EI,Omeife H,Edema T,et al. Microalbuminuria and associated factors in newly diagnosed diabetics[J]. Niger Postgrad Med J,2001,8(4):187-192

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