摘要
Ⅰ. INTRODUCTION Clotting factor Ⅸ is an essential member in the intrinsic clotting pathway, and the deficiency of factor Ⅸ may cause hemophilia B. An important subject on gene therapy for hemophilia B is to increase the protein products of factor Ⅸ in human cells. In our earlier studies, we have constructed several recombinant retroviral vectors with factor
基金
This work was supported by a grant from National High Technology Program 863-102-17-40.