摘要
In order to explore this type of <sup>99m</sup>Tc-GH and N<sub>2</sub>S<sub>2</sub> ligands exchange reaction as a common method for the preparation of <sup>99m</sup>Tc-N<sub>2</sub>S<sub>2</sub> complexes, detailed kinetic study of ligand exchange reaction between <sup>99m</sup>Tc-GH and ECD was carried out. This paper presents preliminary results from the study at different ligand concentrations and pH values. The ligand exchange reaction is a second order reaction. Its rate constant being pH dependent were determined as: k<sub>pH2</sub>=1.11×104 l.mol<sup>-1</sup>. min<sup>-1</sup>, k<sub>pH5</sub>=1.34×10<sup>4</sup> l.mol<sup>-1</sup> min<sup>-1</sup>, kpH6=2.24×10<sup>4</sup> l. mol<sup>-1</sup>.min<sup>-1</sup>.
In order to explore this type of ^(99m)Tc-GH and N_2S_2 ligands exchange reaction as a common method for the preparation of ^(99m)Tc-N_2S_2 complexes, detailed kinetic study of ligand exchange reaction between ^(99m)Tc-GH and ECD was carried out. This paper presents preliminary results from the study at different ligand concentrations and pH values. The ligand exchange reaction is a second order reaction. Its rate constant being pH dependent were determined as: k_(pH2)=1.11×104 l.mol^(-1). min^(-1), k_(pH5)=1.34×10~4 l.mol^(-1) min^(-1), kpH6=2.24×10~4 l. mol^(-1).min^(-1).
