呼吸肌锻炼对慢性阻塞性肺疾病缓解期患者肺功能及生活质量的影响

Effect of respiratory muscle training on pulmonary function and quality of life in patients with chronic obstructive pulmonary diseases in remission period

目的:探讨呼吸肌锻炼对慢性阻塞性肺疾病(chronicobstructivepulmonarydisease,COPD)缓解期患者肺功能及生活质量的影响。方法:COPD缓解期患者64例,随机分2组,对照组患者吸入0.25g/L溴化异丙托品气雾剂40μg,2次/d。观察组患者吸入0.25g/L溴化异丙托品并行呼吸肌锻炼,疗程6个月,治疗前及治疗后6个月分别进行肺功能测定及生活质量评分。结果:观察组用力肺活量(forcedvitalcapacity,FVC),FVC占预计值%(FVC%)、第1秒用力呼气容积(forcedexpiratoryvolumeinthefirstsecond,FEV1)、FEV1占预计值%(FEV1%)及FEV1/FVC均明显高于治疗前(t=2.12～2.43,P<0.05)。观察组患者治疗后生活质量较治疗前后明显提高(t=4.72～6.18,P<0.01)。结论:呼吸肌锻炼能改善COPD患者的肺功能及提高生活质量。

AIM:To explore the effects of respiratory muscle training on pulmonary function and quality of life(QOL) in patients with chronic obstructive pulmonary diseases(COPD) in remission period. METHODS:Sixty four COPD patients in remission period were randomly divided into two groups:control group[treated with aspiration of 40 μg atrovent aerosol(0.25 g/L),twice a day] and observation group[treated with aspiration of atrovent aerosol(0.25 g/L) and respiratory muscle training],and the therapeutic course was six months.Pulmonary function and QOL were evaluated remission before and 6 months after treatment. RESULTS:The forced vital capacity(FVC),predictive rate of FVC(FVC%),forced expiratory volume in 1 s(FEV1),predictive rate of FVE1 (FVE1%) and FVC/ FEV1 in the observation group were all obviously higher than those in the control group(t=2.12-2.43,P< 0.05).QOL in the observation group after treatment was significantly improved as compared with that before treatment(t=4.72-6.18,P< 0.01). CONCLUSION:Respiratory muscle training can improve the pulmonary function and QOL of COPD patients.