影响康复期精神分裂症患者自测健康的相关因素分析

Analysis of related factors of self rated health measurement in patients with schizophrenia during rehabilitation period

目的:了解影响康复期精神分裂症患者自测健康的有关因素。方法:采用自测健康评定量表(self-ratedhealthmeasurementsscale,SRHMS)简明精神病评定量表(BPRS),阴性症状评定量表(SANS),阳性症状评定量表(SAPS),住院精神病人康复疗效评定量表(IPROS),对康复期精神分裂症患者(n=210)和一般人群(n=240)进行评定分析。结果:康复期精神分裂症患者的生理健康子量表分,心理健康子量表分,社会健康子量表分以及自测健康量表总分低于一般人群,SRHMS各因子分及总分在两组之间的差异存在显著的意义(u=-2.3841～-8.1856,P<0.05～0.001)。康复期精神分裂症组的SRHMS总分与病程、住院时间、药物剂量、SANS总分、IPROS总分、BPRS总分等成显著负相关(r=-0.250～-0.144,P<0.05～0.01);逐步回归分析显示药物剂量是影响康复期精神分裂症组患者自测健康的主要因素。结论:康复期精神分裂症患者的生理健康因子、心理健康因子以及社会健康因子均存在较严重缺陷,主要的影响因素是药物剂量。

AIM:To explore the factors related to self rated health measurement of patients with schizophrenia during rehabilitation period. METHODS:Patients with schizophrenia during rehabilitation period(n=210) and normal people(n=240) were evaluated by self rated health measurement scale(SRHMS),brief psychiatric rating scale(BPRS),scale for the assessment of negative symptoms(SANS),scale for the assessment of positive symptoms(SAPS) and inpatient psychiatric rehabilitation outcome scale(IPROS). RESULTS:The subscale scores of physiological health,psychological health,social health and total score of SRHMS in the schizophrenia group were lower than those in the control group,and there were significant differences in factor scores and total scores of SRHMS between the two groups(u=-2.384 1--8.185 6,P< 0.05-0.001).In the schizophrenia group,the total score of SRHMS was significantly and negatively related with disease course,duration of hospitalization,drug dosage, total scores of SANS,IPROS and BPRS(r=-0.250--0.144,P< 0.05-0.01). Stepwise regression analysis indicated that the drug dosage was the main factor that affected the self rated health measurement of schizophrenia patients during rehabilitation period. CONCLUSION:There are much more serious deficiencies in the factors of physiological health,psychological health and social health of patients with schizophrenia during rehabilitation period,and the mainly affecting factor is drug dosage.