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α_2HS-糖蛋白、α_1-抗胰蛋白酶和GC的同步分型与应用 被引量:2

SIMULTANEOUS PHENOTYPING OF AHSG,PI AND GC WITH IEF AND PATERNITY TEST
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摘要 作者应用等电聚焦技术,建立了同步检测α_2HS-糖蛋白表型,α_1-抗胰蛋白酶亚型和GC亚型的方法。本法累计个人识别机率为0.9701,累计非父排除率为0.5811、是国内外同步电泳分型史鉴别效率最高的方法。在11例亲子鉴定中应用本法取得了满意结果。 Simultaneous phenotyping of AHSG, Pi and GC by IEF is reported. The results showed that the cumulative discrimination power and the cumulative exclusion probability of paternity of this method were 0.9701 and 0.58.11 respectively. It was proved to be the most efficient method for individual identification among the simultaneous phenotypings of genetic markers.It has been applied to paternity test and the results were satisfactory.
出处 《中国法医学杂志》 CSCD 1992年第3期138-140,194,共4页 Chinese Journal of Forensic Medicine
基金 国家自然科学基金~~
关键词 α<sub>2</sub>HS-糖蛋白 α<sub>1</sub>-抗胰蛋白酶 GC 等电聚焦 同步电泳分型 遗传多态性 亲子鉴定 α2-HS-glycoprotein α1-antitrypsin Group-specific component Isoelectric focusing Genetic polymorphism Simultaneous phenotyping
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参考文献6

  • 1侯一平,芶清,吴梅筠.成都地区汉族人群α2HS-糖蛋白的遗传多态性[J].华西医科大学学报,1991,22(4):348-351. 被引量:2
  • 2侯一平,吴梅筠.抗GC血清的制备及鉴定[J].中国法医学杂志,1989,4(4):193-195. 被引量:3
  • 3黄力力,李伯龄,周静,邱宁.及 GLOⅠ型的研究[J]中国法医学杂志,1988(02).
  • 4Westwood SA.The use of α2 HS-glycoprotein and group specific component in typing forensic blood samples for discriminative and investigative purposes. Electrophoresis . 1988
  • 5Yuasa I,et al.Genetic polymorphism of human α2 HS-glycoprotein:characterization and application to forensic hemogenetics. Electrophoresis . 1988
  • 6Constans J,et al.The group specific component/vitamin D binding protejn(GC/DBP) system in the analysis of disputed paternities. Electrophoresis . 1988

二级参考文献1

  • 1李伯令,人类血液和血斑的法医个人识别手册,1988年

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