云南高山型地区血吸虫病防治措施的研究

STUDIES ON CONTROL MEASURES OF SCHISTOSOMIASIS IN MOUNTAINOUS REGIONS, YUNNAN PROVINCE

1986～1990年,根据山区血吸虫病流行特点,在不同流行程度的4个行政村分别采用群体化疗辅以感染螺点灭螺(A_1村)、单纯群体化疗(A_2村)、阳性人群化疗辅以感染螺点灭螺(B_1村)和单纯阳性人群化疗(B_2村)。结果A_1、A_2、B_1和B_2村的居民感染率分别下降88.71％、91.37％、86.18％和87.07％;儿童感染率分别下降89.47％、89.71％、78.83％和69.48％;病人EPD分别下降94.0％、95.6％、93.8％和94.4％;哨区感染螺平均密度分别下降97.30％、86.67％、100％和0,证明采用以化疗为主导的防治措施是可行的。

According to the epidemiologic characteristics of mountainous schistosomiasis, several kinds of treatment were used in 4 villages in different endemic levels from 1986 to 1990. Mass chemotherapy with praziquantel and focal mollusciciding, and single mass chemotherapy without focal mollusciciding were conducted in village A1 and A2 respectively. In village BI selective chemotherapy was used for positive inhabitants with focal mollusciciding and in village BZ only positive inhabitants were treated without mollusciciding. The results show that in village A1; A2, B1 and B2 the infection rate of inhabitants decreased from 38. 1%, 36. 5%, 9. 3% and 17. 2% to 4. 3%, 3. 2%, 1. 3% and 2. 2% respectively, and the rate of infected children had dropped 89. 47%, 89. 71%, 78. 83% and 69. 48%. EPD of patients dropped 94. 0%, 95. 6%, 93. 8% and 94. 4% and the rate of infected snails dropped 95. 54%. 65.91%, 100% and 0% respectively in these villages. All of these evidences express that using chemotherapy as a dominant control measure in mountainous endemic regions is available.