乙型肝炎疫苗和卡介苗同时或分别接种的免疫应答

Immune Responses of Respective or Simultaneous Administration of Hepatitis B Vaccine and BCG

作者应用乙肝疫苗和卡介苗同时或分别接种不同月龄婴儿,结果表明,同时与分别接种的免疫应答类似,临床反应均轻微。但接种儿童月龄较大 PPD 阳转率较高,平均硬结直径较大,抗-HBs 的 GMT 较高。

The interactions of hepatitis B (HB) vaccine with BCG and immune response of re-spective administration of these vaccines in various months of age were studied.The results showedthat clinical reactions of all vaccines were mild.The immune responses to the simutaneous inoculationof HB vaccine and BCG were similar to the immune responses observed after administration of eachvaccine alone.It is concluded that HB vaccine and BCG can be immunized at the same time.In addi-tion,we found that conversion rates and diameters of the induration of local reaction at the inoculationsites after PPD test and the levels of anti-HBs were related to month of age of the vacinees.