新生儿肺透明膜病急性期并发症临床分析

CLINICAL ANALYSIS OF THE COMPLICATIONS IN HYALINE MEMBRANE DISEASE

本文分析了48例不同程度新生儿肺透明膜病急性期并发应,所有病例均用呼吸机以间歇指令/呼气末正压方式进行通气。存活共36例。48例中43例有并发症。主要并发症有气压伤(16.8％),脑室内出血(31.3％),动脉导管开放(41％)及医院内获得感染(31.4％)。12例同时存在2种并发症,5例存在3种并发症。严重肺透明膜病的主要并发症为气压伤。并发症的发生有一定的时间顺序和诱因,早期认识,预防及治疗并发症将改善其预后。

Analysis of the acute complications in Hyaline Membrane Disease (HMD) of the newborn was made in 48 cases of varying severity. All cases were ventilated with intermittent mandatory ventilion and positive end-expiratory pressure. Among them 36 cases were cured. There were complications in 43 of the 48 cases.The main complications were baro- trauma (16.8%) , intraventricular hemorrhage (31.3%), patent ductus ar- tcriosus (41%) and nosocomial infections (31.4%).In 12 cases 2 complica- tions were found together and in 5 there were 3 complications. Barotrauma was seen mainly in those with sereve HMD. Complications were observed to follow a definite sequece and inducemenets. Early recognition, preven- tion and treatment of these complications will improve the outcome.