新生儿感染性肺炎血清生长激素的测定探讨

THE DETECTION OF THE SERUM GH IN THE NEONATES WITH INFECTIVE PNEUMONIA

我们应用放射免疫分析法测定了新生儿感染性肺炎患者及同期正常新生儿血清生长激素水平。结果发现:新生儿感染性肺炎患者急性期、缓解期及痊愈时血清生长激素水平均低于正常新生儿(P均<0.001),且缓解期比急性期更低(P<0.001),痊愈时虽比缓解期略高,但无统计学意义(P<0.05)。表明新生儿感染性肺炎时垂体分泌生长激素受到抑制,原因尚不明。

The serum GH Levels of infective pneumonia patients were detected with RIA and health neonates were compared. The author found that the serum GH of the patients were remarkable lower in the acute, remission and recovery stage than in the health neonates. There is significant di- fference between these two groups (P all<0.001). In addition, the serum GH of the remission stage of patients were much lover than in the acute stage (P<0.001), and slight lower than in the recouery. However, the difference was not statistically significant (P>0.05). The author conjec- tures that the secretion of the GH secreted by pituitary in the patients might be inhibited.