24例真菌菌血症的临床及病原学分析

Clinical and Pathogenetic Analysis of 24 Cares of Fungemia

本文报告由酵母菌引起的真菌血症24例,皆由血培养证实。病原菌不少于10种,70.8％为念珠菌,但白色念球菌仅4株。本组病人的大部分有严重的基础病。24例中10例为血液病,7例是心血管及腹部手术后,1例是先天免疫缺陷症,其他6例。9例死亡(死亡率37.5％)。结果表明,两性霉素B及咪康唑治疗有效。

This paper reports 24 cases of fungemia caused by yeasts, which were confirmed by blood cultures. The pathogens belongs to at least 10 species and 70.8% of them are Candida spp., with only 4 Candida albican strains. Most of the patients had serious underlying diseases. Of the 24 cases, 10were hemotopathy, 7 had cardiovascular or abdominal operation, I was congen- ital immunodeficiency syndrome patient, and 6 others. 9 of them were dead(mortality 37.5%). In addition, our results suggests that Amphotericin B and Miconazole were effective for the treatment of fungemia.