摘要
57例垂体大泌乳素癌中15例行单纯放疗,42例行手术加放疗。放疗采用^(60)C。或直线加速器,照射剂量40～55Gy/5～7W。随访0.5～13年后大多数患者临床症状得到控制或改善。血浆PRL水平与肿瘤残留或复发里正相关,与月经恢复呈负相关。22.8％患者血浆PRL降至正常范围内。随着时间的延长垂体功能低下率逐渐增加。
Fifty-seven patients with pituitary macro-prolactinoma were treated; 15 by conventional radiotherapy alone and 42 by partial resection followed by radiotherapy. The tumor dose ranged 40-55 Gy/5~7wk. The follow-up time was 0. 5-13 years. In most patients the symptoms disappeared or improved. The plasma prolactine(PRL)was reduced to normal in only 22. 8% of patients. The PRL level was positively related with residual tumor or relapse but was negatively correlated with recovery of menstruation. Yet,the frequency of hypopituitarism increased with time. The authors believe that patients with pituitary macro-prolactinoma should be closely followed with radio-immunal as say and CT for hypopituitarism and relapse.
出处
《中华放射肿瘤学杂志》
CSCD
1992年第1期19-21,67,共4页
Chinese Journal of Radiation Oncology
