摘要
1983年至1986年我院共收治NHL324例,随访到1989年6月,110例死亡,其中临床Ⅰ期8例,Ⅱ期17例,19例疗中由ⅠⅡ期进展为Ⅲ、Ⅳ期,Ⅲ期17例,Ⅳ期49例.50例伴有全身症状.ⅠⅡ期以局部扩大野放疗为主,部分病例做腹部预防照射。Ⅲ Ⅳ期以化疗为主。分析ⅠⅡ期疗失败的原因:Ⅰ.临床表现为高度进展性,2.早期播散倾向,3.原发于韦氏环的病例、腹部预防照射仅能预防腹腔复发,仍可出现腹腔以外部位复发,4.个别病例表现为放射抗拒性.Ⅲ、Ⅳ期治疗失败的原因与治疗毒性反应和没能使用较强的化疗方案有关。
From 1983 to 1986,324 NHL patients were treated and followed to June 1989. Stage Ⅰ and Ⅱlesions were treated with extended field irradiation (EFT) and stage Ⅲ and Ⅳ lesions were chiefly treated with chemotherapy. 110 patients have died during follow-up. Cause of failure in Stage Ⅰ and Ⅱ patients were: 1. Highly progressive disease, 2. Early disseminating tendency, 3. For NHL in the Waldeyer's ring, abdominal prophylactic irradiation did prevent intra-abdominal recurrence but extra-abdominal recrudescence may still occur,and 4. Some lesions were radio-ressJstant. Toxicity of drugs and conservative chemotherapy were related to failure in Stage Ⅲ and Ⅳ lesions.
出处
《中华放射肿瘤学杂志》
CSCD
1992年第1期32-35,68-69,共6页
Chinese Journal of Radiation Oncology
