90例子宫胎盘绒毛良恶性病变AgNOR的研究

A study of AgNOR on benign and malignant lesions for 90 cases uteri and chorions

用AgNOR定量法,对90例子宫不同部位(子宫颈、子宫肌壁、子宫内膜)及胎盘绒毛的良恶性病变进行了研究。结果表明,子宫各部及胎盘绒毛良恶性病变之间AgNOR均数比较有显著性差异,P均<0.001。同时提示在刮宫标本,区分侵袭性葡萄胎与葡萄胎是可能的。作者将AgNORs分为4种形态:小圆形、大圆形、粗颗粒形及聚合形。AgNORs在核区内分布形式有:核仁内型和散在型。并指出AgNORs的形态及其分布形式与病变性质有关。

Using a silver staing technique, AgNOR was quantitatively studied in benign and malignant lesions for 90 cases uteri and chorions. The result showed that the mean numbers of AgNORs of benign and malignant lesions for various parts have significant difference,p all <0.001.Simultanously,the result suggested that it is possible to distinguish invasive mole from hydatidiforme mole with curettage specimen.The AgNORs can be divided into four classes, small round shape,large round shape,gross granule shape and aggregation shape.The distribution of AgNORs in the nuclei have two types, congregation within the nucleolus and dispressed through the nuclei.The shapes and the distribution of AgNORs in the nuclei are related to quality of the lesions.