农村妇女放置四种宫内节育器的远期使用效果评价

The Evaluation of Leng-Term Effect on Performance of 4 Different IUD in Women in Rural Areas.

本研究平行对比了不锈钢宫形器、不锈钢单环、MLCu250和TCu220C四种IUD在农村妇女中的使用效果。对分娩后3～9个月自愿采取避孕措施的哺乳期妇女711名,用实验流行病学方法严格控制有关干扰因素,用单盲法随机进入各组。6年末随访结果表明:不锈钢单环累计存放率最低,为31.15%,与其它三种IUD间有极显著差异(P【0.01)。宫形器、MLCu250和TCu220C的存放率则分别为54.21%、53.95%和52.49%。第7年取出正常使用的20例MLCu250的铜溶蚀量评估表明:铜溶蚀受沉积物量的影响,其使用期限至少6年。MLCu250带器妊娠率低而TCu220C脱落较少;宫形器则成本低副作用小,长期放置安全有效。

This is an experimental epidemiologic study comparing the performance of stainless steel ring(SSR) uterine cavity-shaped device (UCD), MC Cu250 and TCu220C in women in rural areas,711 healthy women, para 1 and gravida 1, 22-32 years of age, 3-9months post-partum were randomized to 4 groups receiving 4 different devices single- blindedly. They were followed up regularly and complated in 6 years. The results showed that the crude cumulative continuation rate of SSR was 31. 15%.significantly lower than those of the other 31-UDs(P<0. 01). The continuation rate of UCD.MLCu250 and TCu220C were 54. 21%, 53. 95% and 52. 49%.respectively. The residue amount of copper in 20 MLCu250 removed from the subjects wearing for 73 months indicated that the quantity of deposits can significantly affect the rate of copper corrosion, and the using term of MLCu250 can exceed 6 years at least. MLCu250 had lower pregnancy with IUD in situ and TCu220C was Jess expulsion. It is worth mentioned that UCD had the advantages of low price, less side-effects, longer using period, safer and more effective.