15例良性牙骨质母细胞瘤的临床、X线和病理三结合分析

BENIGN CEMENTOBLSTOMA: A CLINICAL-RADIOLOGICAL-PATKOLOGICAL STUDY OF 15 CASES

从临床、X线、病理三方面分析了15例BCB的特征,并对4例作BMP—McAh免疫组化染色,结果表明BCB多见于15—25岁,多位于前磨牙和磨牙区,X线表现为附着牙根,周围绕以“包膜”的斑点状或致密团块,镜下由牙骨质样物质和牙骨质母细胞构成,BMP—McAb染色牙骨质母细胞和新形成、未钙化的牙骨质样物质呈强阳性。本文着重讨论了BCB和BOB的鉴别,强调BCB的诊断必须遵循三结合原则。

Fifteen cases benign cementoblastoma were analyzed with regard to clinical, radiological and histological features, and immunohistochemical stain of BMP-McAb for 4 cases were also presented.The result indicates that most cases occured in patients between 15 to 25 years and the typical site was in the premolar/molar region.Radiological finding exhibited a mottled or dense mass attached to the tooth root outlined by a narrow, well-delineated peripheral radiolucency.Under microscope, the tumour was composed of osteocementum and cementoblast.The cementoblast and the newly formed, uncalcified osteocementum showed strong positive for BMP-McAb stain.The authers also discussed the differential diagnosis between benign cementoblastoma and benign osteoblastoma, and emphasized the importance of combination of clinical, radiological, and histopathologic characteristics in diagnosis.