摘要
作者采用免疫扩散法,测定40例正常健康人和80例急性细菌性肺炎患者的血浆纤维结合蛋白(Plasma fibronectin,PFn)。结果表明:急性细菌性肺炎患者的PFn(214.49±77.84μg/ml)低于正常健康人(292.48±43.11μg/ml),两者间有极显著性差异(P<0.001)。患者中,10例重型急性细菌性肺炎患者的PFn(127.45±31.02μg/ml)显著低于20例轻中型急性细菌性肺炎患者(255.11±54.16μg/ml),两者间有极显著性差异(P<0.001);11例急性细菌性肺炎患者恢复期的PFn(213.13±41.32μg/ml)较急性期(154.52±51.27μg/ml)明显升高(P<0.001)。作者认为,血浆PFn的含量可作为判定急性细菌性肺炎患者病情和预后的一项指标。
Plasma fibronectin (PFn)level was measured with immunoelectropho-resis in 40 healthy adults and 30 patientswith acute bacterial pneumonia. Theresults showed that PFn was considerablylowered in acute bacterial pneumonia(214.49±77.84μg/ml) when compared withthat of healthy controls (292.48±43.11μg/ml), (P<0.001). In the pneumonia group(10severe cases) the level of PFn was signifi-cantly lowered than that in the moderateor mild cases (127.45±31.03μg/ml vs.255.11±54.16μg/ml), (P<0. 001). In 11 cases-of recovering pneumonia, PFn was signifi-cantly higher than that in exacerbationperiod(213.13±41.32μg/ml vs. 154.52±51.27μg/ml) (P<0.001). We think that PFn level is helpful toevaluate the clinical course and prognosisof acute bacterial pneumonia.
出处
《华西医科大学学报》
CSCD
1992年第1期91-93,共3页
Journal of West China University of Medical Sciences