摘要
龙胆泻肝汤对醋酸所致小鼠毛细血管通透性增高及大鼠蛋清性足肿胀均有显著抑制作用,并能抑制大鼠被动皮肤过敏反应和豚鼠过敏性休克,体内外实验表明对乙型链球菌感染的小鼠也有一定的保护效果。
The pharmacological study on Longdan Xiegan decoction were observed.The results were follows:1. Antiinflammatory Effects:( 1 )The decoction could inhibit the increase in capi-llarypermeability caused by acetic acid ip in mice.(2)The decoction markedly decreased swollen induced by egg albumin on rats.2.Antihypersensitive effects:The decoction inhibited passive cutaneous anaphylaxis on rats .and protected guine pig f rom anaphylactic shoc k. 3. In vitro test, the decoction showed certain bacteriostatic activity against streptococcus hemolyticus. In vivo test,the decoction could decrease death rate of mice infected by streptococcushemolyticus.4.The decoction neither induced any change in spleen and thym-usweight on mice,nor induced any change of phagocytosis of the phagocytes of mice.
出处
《中药药理与临床》
CAS
CSCD
1991年第1期5-7,共3页
Pharmacology and Clinics of Chinese Materia Medica
关键词
龙胆泻肝汤
抗炎
抗变态反应
抑菌
Longdan Xiegan decoction
antiinflammatory
antihypersensitive
bacteriostatic activity
