STUDY ON THE EFFECTS OF THE ANTITUMOR DRUG cis-DDP ON THE PHASE BEHAVIOR OF DPPC LIPOSOMES AND MOLECULAR MECHANISM OF THE INTERACTION

STUDY ON THE EFFECTS OF THE ANTITUMOR DRUG cis-DDP ON THE PHASE BEHAVIOR OF DPPC LIPOSOMES AND MOLECULAR MECHANISM OF THE INTERACTION

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摘要 Cis-diamminedichloroplatinum (Ⅱ) (cis-DDP, also cisplatin) is the first heavy metal coordination compound to be the leading and most widely used antitumor drug.The molecular structures of cis-DDP and trans-DDP (inactive) are shown to be:

作者沈子威孙中平赵南明

机构地区 Department of Biological Science and Biotechnology

出处《Chinese Science Bulletin》 SCIE EI CAS 1991年第2期149-153,共5页

关键词 cis-DDP DPPC liposomes ammine LIGANDS phosphofipids. CIS-DDP DPPC LIPOSOMES AMMINE LIGANDS PHOSPHOLIPIDS

分类号 N [自然科学总论]

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Chinese Science Bulletin

1991年第2期

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STUDY ON THE EFFECTS OF THE ANTITUMOR DRUG cis-DDP ON THE PHASE BEHAVIOR OF DPPC LIPOSOMES AND MOLECULAR MECHANISM OF THE INTERACTION

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