PREPARATION OF POLYVINYLAMINE LIGAND EXCHANGE RESIN GRAFTED WITH L-PROLIN

Chiral ligand polymers are the efficient stationary phases of liquid chromatography for the resolution of DL-amino acids and are of great advantages for studying the mechanism of chiral recognition of the polymer. Up to now, the supporters used for resolution of DL-amino acids are based on polystyrene, polyacrylanide, polymethacrylate and polyvinylpyridine. We obtained a new chiral resin by grafting L-Pro on the polyvinylamine and then complexing it with Cu(Ⅱ) which could be used as a supporter of liquid chromatography to resolve DL-Phe, His, Tryp. The factors affecting the functional reactions are also discussed.

<正> Chiral ligand polymers are the efficient stationary phases of liquid chromatography for the resolution of DL-amino acids and are of great advantages for studying the mechanism of chiral recognition of the polymer. Up to now, the supporters used for resolution of DL-amino acids are based on polystyrene, polyacrylanide, polymethacrylate and polyvinylpyridine. We obtained a new chiral resin by grafting L-Pro on the polyvinylamine and then complexing it with Cu(Ⅱ) which could be used as a supporter of liquid chromatography to resolve DL-Phe, His, Tryp. The factors affecting the functional reactions are also discussed.