摘要
pppA2＇p5＇A2＇p5＇A （briefly 2＇-5＇P<sub>3</sub>A<sub>3</sub>） and its homologues （2＇-5＇P<sub>3</sub>A<sub>n</sub>, n≥2） are induced by interferon （IFN）, and play an important role in the IFN action. In 1985, Li and Liu demonstrated the existence of specific receptor for 2＇-5＇P<sub>3</sub>A<sub>3</sub> on the surface of macrophages. This is the first receptor for an oligonucleotide and opens up a
