CPK—MB增高、CPK不高在急性心肌梗塞中的意义

Significance of elevated Creatine Kinase MB with normal Creatine Kinase in Acute Myocardial Infaction

在50名住院AMI患者中探讨了CPK—MB升高,CPK不高的临床意义。根据CPK及CPK—MB水平患者分成四组:CPK、CPK—MB均增高组(组Ⅰ);CPK不高,CPK—MB增高组(组Ⅱ);CPK增高,CPK—MB不高组(组Ⅲ);CPK及CPK—MB均正常组(组Ⅳ)。CPK—MB升高、CPK不高的发生率在本组为10％。本文比较了组Ⅱ与组Ⅰ中小面积心肌梗塞的CPK及CPK—MB,发现两者的CPK基础值及CPK峰值有显著性差异,提示组Ⅱ患者的CPK基础值较低。本文认为CPK—MB升高,CPK不高提示心梗范围较小。

The significance of elevated creatine kinase MB(CPK—MB)with normal creatine kinase (CPK) in acute myocardial infaction (AMI)was discussed in 50 AMI hospitalized patients. According to the levels of CPK and CPK—MB, these patient were divied into four subgroups. In our study a tehth park of patients was in subgroup 2 (only CPM—MB elevated). Comparing the levels of CPM—MB and CPK in subgroup 2 with those of patient in subgroup 1 (both CPK and CPK—MB elevated),whose infaction aera were smaller. It was foud that there was a significant difference between two subgroups in the levels of basic and peak CPK. In subgroup 2 the basic CPK was more lower. It may be concluded that the elevated CPK—MB with normal CPK might indicate a small sie of infaction aera in AMI patients.