单纯放射治疗阴茎癌的远期效果——附44例临床分析

LONG-TERM RESULTS OF RADIATION THERAPY FOR CARCINOMA OF THE PENIS

本文回顾性分析我院1958年到1984年底单纯放射治疗阴茎癌44例的远期效果。 材料与方法 患者年龄:23～67岁,平均年龄40.2岁。 患者病程1个月～15年,发病1年以内就诊者占73％（32/44）。患者中包茎、包皮过长者91％（40/44）。包皮龟头炎占57％（25/44）。肿瘤位于龟头者占43％（19/44）,冠状沟30％（13/44）,包皮内板27％（12/44）。 病理诊断:全组中鳞癌38例（86％）,癌末分型2例,无病理4例,均为晚期病例,其中T4N3

Fourty-four patients with carcinoma of the penis treated by radiotherapy alone from 1958 through 1984 were retrospectively analysed. The 5-, 10-, 20-, 30-year survival rates and tumor-free survival rates were. 66%(29/44), 61%(27/44), 60%(25/42), 55%(23/42) 49%(16/33), 49%(16/33), and 43% (3/7), 43% (3/7) respectively. The main factors influencing the long-term results were clinical stage and tumor response to radiation. For 22 patients with early lesions (T1-2, N0) the 5-year survival rates were 100%(22/ 22), but that of 22 patients with advanced lesions was only 32%(7/22). Furthermore, the 5-year survival rates of CR, PR and NC were 93%(28/30), 8%(1/13) and 0(0/1) respectively. The differences are all sigificant (P<0.01). In penile carcinoma, the main cause of failure after radiotherapy was local recurrence and uncontrol. The inguinal node metastasis stood second and distant metastasis was rate.