摘要
副鼻窦癌在美国很少见,年发病率约为1/100000。由于发病隐匿,在诊断时往往已到中晚期。而副鼻窦又邻近重要器官,如眼眶、颅底、脑,彻底的肿瘤切除较为困难,满意的放疗设计也受到限制。所以,中晚期副鼻窦癌的治疗十分棘手。本文是回顾性分析,着重研究上颌窦癌的术后放疗。
73 maxillary sinus carcinoma patients were treated by surgery followed by-postoperative radiotherapy. The 5- and 10-year disease free survivals were 64% and 52%.The prognostic factors were. NO lesions and absence of nerve invasion in pathologic examination of the resected specimen. 78% of patients had good local control. Patients with nerve invasion tended to lead to more local failure. The cervical lymph node was positive in 30% of patients, predominantly in patients with squamous and undifferentiated carcinoma. 23% of patients developed distant metastases, mostly in the lung. Non-squamous cell carcinoma, positive nodes and patients without elective neck irradiation were apt to develop metastasis. The complications were radiation injury to the eye and brain radiation necrosis. The authors believe that combination of surgery and radiation therapy is the best treatment of cancer of the maxillary sinus.
出处
《中华放射肿瘤学杂志》
CSCD
1991年第3期19-23,共5页
Chinese Journal of Radiation Oncology
基金
美国国立癌症研究所基金CA06294
CA16672
