The Triangle-relationship of β-lactam Antitiotics

The Triangle-relationship of β-lactam Antitiotics

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摘要 The geometric parameters for D-Ala-D-Ala are optimized by MM, the most and next two stable conformations are obtained. According to the interaction model with target emzyme suggested by us, the traingle-relationship of it is obtained. This triangle-relationship could be found in the pharmaceuticals belong to different classes of β-actams also. The geometric parameters for D-Ala-D-Ala are optimized by MM, the most and next two stable conformations are obtained. According to the interaction model with target emzyme suggested by us, the traingle-relationship of it is obtained. This triangle-relationship could be found in the pharmaceuticals belong to different classes of β-actams also.

作者 Jing Jiang LIU Ji Wei TANG Min Hui ZHU Xiao Ling FAN

机构地区 Department of Chemistry Institute of Electronics

出处《Chinese Chemical Letters》 SCIE CAS CSCD 1991年第8期653-654,共2页 中国化学快报(英文版)

基金 Project supported by National Scientific Foundation of China

关键词 The Triangle-relationship of lactam Antitiotics

分类号 O6 [理学—化学]

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Chinese Chemical Letters

1991年第8期

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