摘要
目的探讨生长抑素与泮托拉唑钠联合应用治疗急性胰腺炎的临床疗效。方法选取2011年1月~2014年1月舟山市人民医院收治的重症急性胰腺炎(severe acute pancreatitis,SAP)患者124例,随机分为对照组和联合治疗组,每组各62例。对照组给予泮托拉唑钠治疗,联合治疗组给予生长抑素与泮托拉唑钠联合治疗,治疗1周后观察比较2组患者疗效和临床表现。结果治疗后,联合治疗组治疗总有效率为95.16%,明显高于对照组的64.52%,2组比较差异有统计学意义(P<0.05);联合治疗组治疗恢复时间和并发症发生率明显低于对照组,差异均有统计学意义(P<0.05)。结论生长抑素与泮托拉唑钠联合应用能有效提高SAP患者的治疗有效率,缩短患者的病情恢复时间,减少并发症发生。
Objective To explore the efficacy of somatostatin and pantoprazole sodium in treatment of severe acute pancreatitis. Methods 124 cases with severe acute pancreatitis admitted in the People''s Hospital of Zhoushan City from Jan 2011 to Jan 2014 were randomly divided into control group and combination group,each had 62 cases. Patients in control group were treated with pantoprazole sodium,while in combination group were treated with somatostatin and semi Pantoprazole sodium. Results The total effective rate in combination group was 95.16%,higher than 64.52% in control group. the difference was significant(P<0.05 ). The recovery time and the incidence of complication in combination group was significantly lower than control group (P <0.05 ). Conclusion Somatostatin and pantoprazole sodium can effectively improve the treatment efficiency of SAP patients,shorten recovery time,and reduce the incidence of complication.
出处
《中国生化药物杂志》
CAS
北大核心
2014年第3期97-99,102,共3页
Chinese Journal of Biochemical Pharmaceutics
基金
浙江省医药卫生平台骨干人才计划B类(2011RCB020)
