辛伐他汀和阿托伐他汀对冠心病患者的降血脂作用研究

Effect of simvastatin and atorvastatin on reducing blood lipid in patients with coronary heart disease

目的评价辛伐他汀和阿托伐他汀对冠心病患者的降血脂作用。方法选取2013年1月~2014年1月于山东省聊城市第三人民医院收治的150例冠心病患者,采用随机法分为A、B 2组,每组75例。A组患者给予辛伐他汀治疗,B组患者给予阿托伐他汀治疗。比较2组患者治疗前后血脂变化情况。结果治疗后,A、B 2组患者临床症状得到缓解;TC、LDL-C指标均明显下降,与治疗前相比差异有统计学意义(P<0.05);但A、B 2组组间比较差异无统计学意义。结论辛伐他汀和阿托伐他汀均能有效改善患者血脂情况。

Objective To evaluete the effect of atorvastatin on reducing blood lipid in patients with coronary heart disease.Methods 150 cases of coronary heart disease patients collected in Liaocheng Third People’s Hospital of Shandong province from January 2013 to January 2014 were randomly divided into A,B two groups,each had is cases.Group A were treated with simvastatin,and group B were treated with atorvastatin.Blood lipid changes in two groups before and after treatment were compared. Results Compared with before treatment,the clinical sypotoms after treatment in two groups were allivate and TC,LDL-C indexes were significantly decreased (P <0.05 ).But there was no statistical significance between A and B groups. Conclusion Simvastatin and atorvastatin can effectively improve the blood lipid status in patients with coronary heart disease.