西安市某单位体检人群幽门螺杆菌流行病学调查

Epidemiology of Helicobacter pylori in certain unit population in Xi'an

目的了解西安市某单位体检人群幽门螺杆菌(Hp)的感染状况及分布情况。方法采用14 C-尿素呼气试验法(14 C-UBT),检测受检人群548例Hp与14 C结合的每分钟衰变数(DPM),统计不同性别、不同年龄Hp感染情况,分析其影响因素,并提出防控措施。结果 Hp总感染率48.0%(263/548),其中男性Hp感染率47%(191/406),女性Hp感染率50.7%(72/142),两者比较差异无统计学意义(χ2=0.883,P】0.05)。Hp感染阳性率各年龄组间比较差异有统计学意义(χ2=12.495,P【0.05),40~49岁年龄组最高,20~29岁组最低,40~49岁年龄组Hp感染率与20~29岁、30~39岁、50~59岁、】60岁年龄组间两两比较差异均有统计学意义(χ2=5.881~63.835,P【0.05)。结论西安市某单位Hp感染率低于全国平均水平,与性别无关,与年龄有关。

Objective To investigate the infection of Helicobacter pylori(Hp)in certain unit population in Xi'an. Methods 14 C-UBT was adopted to test 14 C disntegration per minute(DPM)for evaluating the infection of Hp. Results 548peoples were enrolled in this study.The total positive rate of Hp infection in all the subjects was 47.9%.The infection rates of Hp in male and female were47%and 50.7%,respectively,without significant difference(P>0.05).The population was divided into 20~29,30~39,40~49,50~59and≥60years group according to the age,and the rate of Hp infection were 47.7%,44.9%,68.4%,50.8% and 45.3%,respectively.There was significant difference between the group of 40~49years of age and other four groups(P<0.05).The highest infection rate of Hp was found in 40~49and the lowest in 20~29group.Conclusion The Hp infection rate in certain unit population in Xi'an is lower than that of the national average.There is significant correlation between Hp infection and age,but not gender.