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压力性尿失禁的干细胞治疗

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摘要 全球约有超过2000万的人罹患尿失禁(urinary incontinence,UI)[1]。在美国约有172万人有尿失禁症状,每年尿失禁治疗的花费超过3200万美元[2]。80岁以上的人群中,女性尿失禁的发病率是男性的2～3倍[3]。20岁以上的女性人群约50%有尿失禁的症状,其中50%为压力性尿失禁(stress urinary incontinence,SUI),其余的为急迫性尿失禁(urge type of UI,UUI,16%)或混合性尿失禁(SUI合并UUI,34%)[4]。急迫性尿失禁是指强烈的尿急症状后立即出现的尿失禁现象,与逼尿肌过度活动(动力性尿急)
作者 伦晓勤 李博
机构地区 济南市济南医院泌尿外科 山东大学附属省立医院泌尿微创中心
出处 《泌尿外科杂志（电子版）》 2014年第2期1-5,73,共6页 Journal of Urology for Clinicians(Electronic Version)
关键词 压力性尿失禁 急迫性尿失禁 干细胞治疗 女性尿失禁 INCONTINENCE 逼尿肌过度活动 urinary 尿急症状 细胞分化 实验报道
分类号 R694.54 [医药卫生—泌尿科学]
  • 相关文献

参考文献11

  • 1Ching-Shwun Lin.Advances in stem cell therapy for the lower urinary tract[J].World Journal of Stem Cells,2010,2(1):1-4. 被引量：5
  • 2Michelle Cruz,Charuspong Dissaranan,Anne Cotleur,Matthew Kiedrowski,Marc Penn,Margot Damaser,Johannes Bitzer.Pelvic Organ Distribution of Mesenchymal Stem Cells Injected Intravenously after Simulated Childbirth Injury in Female Rats[J].Obstetrics and Gynecology International.2011
  • 3Alienor S Gilchrist,Eric S Rovner.Managing complications of slings[J].Current Opinion in Urology.2011(4)
  • 4Ching-Shwun Lin.Stem Cell Therapy for the Bladder—Where Do We Stand?[J].The Journal of Urology.2011(3)
  • 5Xiao Hui Zou,Yun Long Zhi,Xiao Chen,Hang Mei Jin,Lin Lin Wang,Yang Zi Jiang,Zi Yin,Hong Wei Ouyang.Mesenchymal stem cell seeded knitted silk sling for the treatment of stress urinary incontinence[J].Biomaterials.2010(18)
  • 6Francesca Colazzo,Padmini Sarathchandra,Ryszard T. Smolenski,Adrian H. Chester,Yuan-Tsan Tseng,Jan T. Czernuszka,Magdi H. Yacoub,Patricia M. Taylor.Extracellular matrix production by adipose-derived stem cells: Implications for heart valve tissue engineering[J].Biomaterials.2010(1)
  • 7Guiting Lin,Guifang Wang,Lia Banie,Hongxiu Ning,Alan W. Shindel,Thomas M. Fandel,Tom F. Lue,Ching-Shwun Lin.Treatment of stress urinary incontinence with adipose tissue-derived stem cells[J].Cytotherapy.2010(1)
  • 8Xiaoyun Wu,Shili Wang,Baoli Chen,Xinling An.Muscle-derived stem cells: isolation, characterization, differentiation, and application in cell and gene therapy[J].Cell and Tissue Research.2010(3)
  • 9John O.L.DeLancey.Why do women have stress urinary incontinence?[J].Neurourol Urodyn.2010(S1)
  • 10YoshiakiKinebuchi,NaokiAizawa,TetsuyaImamura,OsamuIshizuka,YasuhikoIgawa,OsamuNishizawa.Autologous bone‐marrow‐derived mesenchymal stem cell transplantation into injured rat urethral sphincter[J].International Journal of Urology.2010(4)

二级参考文献33

  • 1Liu J;Huang J;Lin TX.Cell-to-cell contact induces human adipose tissue-derived stromal cells to differentiate into urothelium-like cells in vitro,2009(03).
  • 2Gregory CA,Prockop DJ,Spees JL.Non-hematopoietic bone marrow stem cells: molecular control of expansion and differentiation. Experimental Cell Research . 2005
  • 3Kotaro Yoshimura,Katsujiro Sato,Noriyuki Aoi,Masakazu Kurita,Toshitsugu Hirohi,Kiyonori Harii.Cell-Assisted Lipotransfer for Cosmetic Breast Augmentation: Supportive Use of Adipose-Derived Stem/Stromal Cells[J]. Aesthetic Plastic Surgery . 2008 (1)
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  • 6L. K. Carr,D. Steele,S. Steele,D. Wagner,R. Pruchnic,R. Jankowski,J. Erickson,J. Huard,M. B. Chancellor.1-year follow-up of autologous muscle-derived stem cell injection pilot study to treat stress urinary incontinence[J]. International Urogynecology Journal . 2008 (6)
  • 7H. Strasser,R. Marksteiner,E. Margreiter,M. Mitterberger,G. M. Pinggera,F. Frauscher,M. Fussenegger,K. Kofler,G. Bartsch.Transurethral ultrasonography-guided injection of adult autologous stem cells versus transurethral endoscopic injection of collagen in treatment of urinary incontinence[J]. World Journal of Urology . 2007 (4)
  • 8Teruhiko Yokoyama,Johnny Huard,Michael B. Chancellor.Myoblast therapy for stress urinary incontinence and bladder dysfunction[J]. World Journal of Urology . 2000 (1)
  • 9Huang YC,Shindel AW,Ning H,Lin G,Harraz AM,Wang G,Garcia M,Lue TF,Lin CS.Adipose Derived Stem Cells Ameliorate Hyperlipidemia Associated Detrusor Overactivity in a Rat Model. Journal d Urologie . 2010
  • 10Lin G,Wang G,Banie L,Ning H,Shindel AW,Fandel TM,Lue TF,Lin CS.Treatment of stress urinary incontinence with adipose tissue-derived stem cells. Cytotherapy . 2010

共引文献4

泌尿外科杂志（电子版）
2014年 第2期

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