合并感染的多囊肾病原菌及耐药性调查分析

Studying of the Pathogens and Drug Resistance of the PKD Patients with Infection

目的对合并感染的多囊肾病原菌及耐药性进行分析。方法回顾性分析97例多囊肾合并感染患者的临床资料。结果通过采集到的97例多囊肾感染囊液送检结果得出:病原菌以革兰阴性菌为主,其中前两位分别为大肠埃希菌、肺炎克雷伯菌,其较敏感的抗生素为亚胺培南、美罗培南、厄他培南、呋喃妥因、哌拉西林/他巴唑坦等。结论大肠埃希菌是合并感染多囊肾患者主要的感染病原菌,随着抗生素的普遍使用,病原菌的耐药性也随之增高,临床医生在选用抗生素时应根据尿培养结果,有针对性的合理使用,提高治疗效果。

Objective To study the pathogens and drug resistance of the PKD (polycystic kidney disease ) patients of with infection. Methods We study retrospectively the clinical data of 97 infectious PKD patients. Re-sults Gram-negative bacteria was the main pathogen,and the first two were Escherichia coli,Klebsiella pneu-moniae,which were sensitive to imipenem、meropenem、ertapenem、nitrofurantoin、Piperacillin/Tazobactam,etc. Conclusions Escherichia coli is the main pathogen,drug resistance become more and more serious with the ex-tensively use of antibiotics. We should choose the right antibiotics based on the results of urine culture.