腹腔镜肾上腺切除术治疗原发性醛固酮增多症合并2型糖尿病患者的临床研究

Laparoscopic Adrenalectomy for the Treatment of the Patients with Primary Aldosteronism and Diabetes Mellitus:A Study on the Clinical Result

目的探讨腹腔镜肾上腺切除术治疗合并2型糖尿病的原发性醛固酮增多症患者的临床效果。方法回顾性分析自2013年1月至2013年12月间本单位收治的11例合并2型糖尿病的肾上腺醛固酮瘤(APA)所致原醛症患者,接受腹腔镜患侧肾上腺切除手术前后醛固酮、血压、空腹血钾、空腹血糖的变化情况。结果醛固酮、血压、空腹血糖在术后明显下降,血钾水平明显上升至正常水平(P<0.05)。结论伴2型糖尿病的APA所致原醛症患者行腹腔镜患侧肾上腺切除手术后高血压、低血钾、高血糖得到纠正,可改善该类型患者胰岛素抵抗现象。

Objective To investigate the Clinical result of laparoscopic adrenalectomy for the treatment of di-abetes mellitus associated with primary aldosteronism caused by aldosterone producing adenoma (APA). Meth-ods The pre-operative and post-operative blood pressure,serum aldosteronism,fasting blood glucose and po-tassium of the patients diagnosed as APA were recorded and retrospectively analysed. Results Comparing to the data before the operation,the aldosteron,blood pressure,fasting blood glucose of these patients decreased sig-nificantly and potassium increased significantly after operation(P<0. 05). Conclusions For patients diagnosed as diabetes mellitus associated with primary aldosteronism caused by APA,the symptoms of hypertension,hypo-potasism and insulin resistence can be improved through removing the adrenal gland or the adenoma.