摘要
Diabetes mellitus entails significant health problems worldwide.The pathogenesis of diabetes is multifactorial,resulting from interactions of both genetic and environmental factors that trigger a complex network of pathophysiological events,with metabolic and hemodynamic alterations.In this context,inflammation has emerged as a key pathophysiology mechanism.New pathogenic pathways will provide targets for prevention or future treatments.This review will focus on the implications of inflammation in diabetes mellitus,with special attention to inflammatory cytokines.
Diabetes mellitus entails significant health problems worldwide.The pathogenesis of diabetes is multifactorial,resulting from interactions of both genetic and environmental factors that trigger a complex network of pathophysiological events,with metabolic and hemodynamic alterations.In this context,inflammation has emerged as a key pathophysiology mechanism.New pathogenic pathways will provide targets for prevention or future treatments.This review will focus on the implications of inflammation in diabetes mellitus,with special attention to inflammatory cytokines.
基金
Supported by Ministerio de Ciencia e Innovación(Instituto de Salud Carlos III-Fondo de Investigación Sanitaria),No.PI07/0870 and No.PI10/576
Ministerio de Sanidad y Política Social(Dirección General de Terapias Avanzadas y Trasplante),No.TRA-182
Sociedad Espaola de Nefrología y ACINEF
Research activity by Navarro-González JF is supported by Programa de Intensificación de la Actividad Investigadora,ISCIII/Canarias
