针刺治疗缺血性中风炎症反应机制研究进展

Research progres s in inflammatory reaction mechanisms for acupuncture treatment of ischemic stroke

超过40%的中风患者在发病后1周内死亡或长期遗留中重度残疾，感染引起的炎症反应是导致这一严重后果的主要原因。当患者发生中风后，无论是急性感染或无菌性炎症反应均能导致缺血性中风患者高致死率、高致残率。这类具有致命性的炎症级联反应受到关注，急性期抗炎治疗成为控制病情发展的关键。认识脑缺血后炎症反应的作用机制及药物、针刺、物理治疗等各类抗炎措施的作用，可有效减少发病过程中炎性损伤，降低患者死亡率，改善预后。

More than 40%of stroke patients died within one week after the onset or with long term severe disabilities. Inflammation response caused by infection is the main cause of this serious consequence. Either acute infection or sterile inflammation can result in the high mortality and high disability rates after ischemic stroke . This kind of fatal inflammatory cascade response should be concerned about . Acute anti-inflammatory treatment is the key step for disease control. The anti-inflammatory treatments, including medication, acupuncture and physiotherapy, can effectively reduce the pathogenesis of inflammatory injury, reduce mortality and improve prognosis after cerebral infraction.