摘要
目的:研究淫羊藿提取物对去卵巢大鼠骨密度、骨重量的影响,探讨中医肾主骨理论。方法:取84只雌性大鼠随机分成假手术组、模型组、己烯雌酚组、骨疏康组、淫羊藿提取物高、中、低剂量组7组,每组12只。造模成功后,饲养90 d,开始灌胃90 d后,检测离体骨骨密度、骨重量。结论:淫羊藿提取物可提高去卵巢大鼠离体骨骨密度、增加离体骨湿重、干重。对实验大鼠去卵巢所致骨质疏松症有明显的治疗作用。
Objective:To Studying the effect of Epimedium Extract on bone mineral density、bone weight of some ovariectomized rats,exploring the theory of TCM kidneys bone. Methods:We selected 84 female rats in the study,they were randomly divided into 7 groups:shamed operations group、model group、diethylstilbestrol group、gushukang group 、Epimedium Extract at high 、medium and low dose groups,every group had 12 rats. After success of modeling, we fed rats for 90 days under the same situation and then gavaged for 90 days, detected in vitro bone mineral density, bone weight. Conclusion:The results indicated that the Epimedium Extract could improve ovariectomized rats in vitro bone mineral density, increased in vitro bone wet weight、dry weight. It had a significant therapeutic effect on osteoporosis caused by ovariectomized rats.
出处
《内蒙古医科大学学报》
2013年第6期442-445,共4页
Journal of Inner Mongolia Medical University
基金
内蒙古自治区高等学校科学研究项目(NJZY13432)
关键词
绝经后骨质疏松
去卵巢大鼠
淫羊藿提取物
骨密度
postmenopausal osteoporosis
ovariectomized rats
epimedium extract
bone mineral density
