血乳酸及血肌酐水平测定对重症急性胰腺炎患者的预后评估价值

The prognostic value of serum creatinine levels and blood lactic acid on predicting patients with severe acute pancreatitis

目的 探讨血乳酸及血肌酐水平的测定在重症急性胰腺炎(severe acute pancreatitis,SAP)患者预后评估的临床价值.方法 分析61例SAP患者入住ICU 24h及住院期间总体血乳酸及肌酐水平,根据预后分为生存组(n=39)及死亡组(n=22),分析比较两组患者全血乳酸及肌酐水平与SAP病死率的关系.结果 两组患者在ICU住院期间总体血乳酸水平,生存组(4.32±0.59) mmol/L低于死亡组(10.62±1.33) mmol/L,两组差异有统计学意义(P＜0.05);两组患者在在ICU住院期间总体血肌酐水平,生存组(121.17±12.03) μmol/L低于死亡组(297.54±13.15)μmol/L,两组差异有统计学意义(P＜0.01).血乳酸、血肌酐水平与APACHEⅡ评分明显相关(P＜0.05).结论 血乳酸和肌酐水平对SAP患者预后评估具有一定的临床价值.

Objective To explore the prognostic significance of blood Lactic acid and serum creatinine in serum creatinine levels and blood lactic acid on Predicting patients with severe acute pancreatitis.Methods Serum creatinine and blood lactic acid was tested on the first day,and average blood lactic acid and creatinine levels in 61 patients with severe acute pancreatitis admitted to the ICU which were divided into survival group(n=39) and death group(n=22).according to prognosis.serum creatinine,blood lactic acid,APACHE scores were compared between two groups.Results Compared with survival group,serum creatinine levels and blood lactic acid were higher in death group(P＜0.05),the average levels were slso higher in Icu hospitalization(P＜0.01),blood lactic acid and serum creatinine were highly correlated to APACHE Ⅱ scores(P＜0.05).Conclusion Serum creatinine levels and blood lactic acid Can predichhe nroanosis of patients with severe acute pancreatitis