血液灌流与联合血液透析治疗百草枯中毒疗效比较

Blood Perfusion Combined with Hemodialysis in Treatment of Patients with Paraquat Poisoning

目的:观察血液灌流联合血液透析治疗百草枯中毒患者的疗效,寻找治疗的有效途径。方法:回顾分析血液灌流(HP)与血液灌流加透析(HD)抢救治疗58例急性百草枯中毒患者的疗效。结果:血液灌流加透析联合组患者死亡率、白细胞计数、血肌酐值、血谷丙转氨酶值、血肌酸激酶值等指标均显著低于血液灌流组(P<0.05)。结论:血液灌流联合血液透析是抢救急性百草枯中毒的有效、安全治疗手段。

Objective: To investigate the clinical effects of hemoperfusion combined with hemodialysis in treatment of the patientsd with acute paraquat poisoning. Methods: 28 cases of acute paraquat poisoning were taken with conventional and hemoperfusion treatment. 30 cases were taken with conventional and hemoperfusion treatment and combined with hemodialysis. Results: The efficiency of hemoperfusion combined with hemodialysis treatment were significantly higher than hemoperfusion treatment only. The Mortality and complication of patients by the combination therapy were significantly lower than that of patients by treatment with hemoperfusion only,there was the statistically significance( P < 0. 05). Conclusion: Hemoperfusion combined with hemodialysis are good way to treat the patients with acute paraquat poisoning.