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PANDER与糖脂代谢

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摘要 胰腺衍生因子(pancreatic derived factor,PANDER/FAM3B)是2002年发现的新的细胞因子家族FAM3家族中的一员。目前有关PANDER的研究主要集中在能量代谢特别是糖脂代谢方面,包括对胰岛β细胞功能调控及对肝脏糖脂代谢的影响。最近,也有研究揭示PANDER可能介入了肿瘤的发生发展过程。本文就PANDER与胰岛α及β细胞功能的关系、循环中PANDER水平与肝脏胰岛素抵抗的关系、肝源性PANDER与肝脏糖脂代谢的关系及PANDER与肿瘤发生的关系等多个角度对PANDER的最新研究进展进行系统讨论与综述。
出处 《生理科学进展》 CAS CSCD 北大核心 2013年第6期425-428,共4页 Progress in Physiological Sciences
基金 国家自然科学基金(81170791) 北京市自然科学基金(7122107)资助课题
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