认知疗法对功能性消化不良患者生活质量的影响

Effects of cognitive psychotherapy on the life quality of patients with functional dyspepsia

目的通过辅助认知疗法对功能性消化不良患者的愈后评价,探讨其可能的作用机制。方法 152医院消化科门诊或住院患者68例,随机分为治疗组和对照组各34例,两组均给予莫沙比利5mg,3次/d,埃索美拉唑20 mg,1次/d,共2周,治疗组同时给予认知疗法,对照组给予一般性支持治疗,8周为一疗程。结果 8周后改良Glasgow评分治疗组与对照组相比有显著差异(P<0.05);GQOLI-74评分除物质生活外,8周后治疗组的客观状态总分、躯体功能、心理功能和社会功能评分与对照组比较均有统计学差异;两组有效率分别为88.24%、64.71%,有统计学差别。结论辅助认知疗法可改善功能性消化不良患者的生活质量。

Objective To evaluate the value of cognitive psychotherapy on treatment of functional dyspepsia and explore its possible mechanism. Methods The 68 patients in authors hospital or outpatient were randomly divided into treatment group and control group. The two groups were treated with mosapride 5mg,3 / day,esomeprazole 20mg,1 / day for 2 weeks,simultaneously the treatment group were given with cognitive psychotherapy while the control group with common supportive treatment for 8 weeks. Results After 8 weeks,improved Glasgow score in the treatment group compared with the control group were significantly different( P < 0. 05); GQOLI-74 score of the treatment group compared with the control group except for material life,such as the total objective state,physical function,mental function and social function,there were significant differences; the effective rates were 88. 24%,64. 71% in treatment group and control one,the difference was statistically significant. Conclusion Cognitive psychotherapy may improve the patient's quality of life,reduce recurrence.