复方血栓通联合怡开治疗视网膜静脉栓塞31例临床分析

The efficacy of Xueshuantong and pancreatic kallikrein in treatment of 31 cases of retinal vein embolism

目的探讨复方血栓通联合怡开(胰激肽释放酶)治疗视网膜静脉栓塞的疗效。方法视网膜静脉栓塞62例(62眼),随机分为复方血栓通联合怡开为观察组31例和单纯怡开为对照组31例。观察组患者服用复方血栓通1.5 g+怡开112 U,3次/d。对照组患者服用怡开片112 U,3次/d,两组患者均予维生素及能量合剂,疗程均为2个月。结果观察组:中央静脉栓塞11例,其中显效5例,有效2例,好转2例,无效2例;分支静脉栓塞20例,其中显效13例,有效5例,好转2例,观察组总有效率占94%,无效率占6%。对照组:中央静脉栓塞8例,其中显效1例,有效1例,好转2例,无效4例;分支静脉栓塞23例,其中显效9例,有效7例,好转4例,无效3例,对照组总有效率77%,无效率为23%。两组比较差异有统计学意义(P<0.05)。同时两组均明确显示分支静脉栓塞疗效好于中央静脉栓塞。结论复方血栓通联合怡开治疗视网膜静脉栓塞的疗效可靠,值得临床上进一步推广应用。

Objective To investigate the efficacy of Xueshuantong and pancreatic kallikrein(TPK) tablets in treatment of retinal vein thrombosis.Methods 62 patients with retinal vein thrombosis(62 eyes) were randomly assigned to treatment group(31 cases) treated with Xueshuantong through joint TPK tablets and control group(31 cases) treated with single TPK piece.The patients in treatment group were taken the Xueshuantong through 1.5 g,three times a day and TPK piece 112 U,three times a day.The patients in control group were taken TPK piece 112 U,three times a day.All patients are vitamin and energy mixture,treatment lasted two months.Results In 31 cases of treatment group with central vein thrombosis,markedly effective was found in 5 cases,effective in 2 cases,improved in 2 cases and invalid in 2 cases.In 20 cases of branch vein thrombosis,13 cases were markedly effective,5 cases were effective,2 cases were improved.The total efficiency rate of observation group was 94%.In 31 cases of the control group,8 cases were central vein thrombosis and one case was markedly effective,one case was effective,2 cases were improved and 4 cases were invalid.In 23 cases with branch vein thrombosis,9 cases were markedly effective,7 cases were effective,4 cases were improved and 3 cases were invalid.The total efficiency rate of the control group was 77%.The difference between the two groups was statistically significant(P<0.05).It clearly demonstrated that branch vein thrombosis group was more effective than central than central venous thrombosis group.Conclusion Xueshuantong combine with TPK have reliable efficacy in treatment of retinal vein thrombosis,and is worth to further spread as the use of clinical.