摘要
目的探讨新生儿化脓性脑膜炎的临床特点和治疗转归。方法分析46例新生儿化脓性脑膜炎的临床特点、实验室检查和病原学治疗转归。结果新生儿化脓性脑膜炎最常见症状为反应差、发热和呼吸系统改变。外周血最常见的改变为贫血、白细胞升高和C反应蛋白(CRP)水平升高。B族溶血链球菌(GBS)及大肠埃希菌是最主要的病原。结论新生儿化脓性脑膜炎是新生儿严重感染性疾病之一,发病率和死亡率高。提高病原诊断率非常重要,抗菌药物需根据病原菌药敏试验以及临床经验选用合适抗生素。
@@@@Objective To explore the clinical features and outcomes of neonates with purulent meningitis . Methods The clinical features, laboratory findings, pathogens and short-term outcomes were analyzed in 46 neonates with purulent meningitis . Results The most common symptoms of neonatal purulent meningitis were poor response, fever and respiratory system changes .The most common peripheral blood changes were anemia , increased leukocyte and high lever of C reaction protein (CRP).Group B streptococcus (GBS) and Escherichia coli were the most important pathogens. Conclusion Purulent meningitis is an important cause of morbidity and mortality in neonates.To improve the pathogen diagnosis rate is very important , and it is helpful for using antibiotic reasonably .
出处
《神经病学与神经康复学杂志》
2013年第1期18-21,共4页
Journal of Neurology and Neurorehabilitation
关键词
新生儿
化脓性脑膜炎
病原学诊断
治疗
neonates
purulent meningitis
etiological diagnosis
treatment
