摘要
乙型肝炎相关肝衰竭发病机制复杂,目前临床上缺乏有效的治疗手段.糖皮质激素具有抑制免疫应答、减少炎症介质的产生,发挥强大而迅速的抗内毒素血症作用,同时还能稳定溶酶体膜、保护肝细胞、减轻肝细胞的坏死.糖皮质激素以其特有的生物学特性已在临床广泛应用.该文对糖皮质激素治疗乙型肝炎相关肝衰竭的现状进行综述.
The pathogenesis of hepatitis B-related liver failure is complicated,and there is no effective treatment at present.Glucocorticoid can inhibit the immune response,reduce the production of inflammatory mediator,and also has strong and rapid effect on anti-endotoxin.At the same time glucocorticoid can stabilize the lysosome membrane,protect the liver cell,and reduce the necrosis of liver cell.Glucocorticoids has been widely used in clinical practice by its unique biological characteristics.In this paper,the research progress of glucocorticoid treatment for hepatitis B-related liver failure is discussed.
出处
《国际流行病学传染病学杂志》
CAS
2013年第3期-,共4页
International Journal of Epidemiology and Infectious Disease
