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嗅觉神经元凋亡相关因子研究

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摘要 成年哺乳动物的嗅觉受体神经元(olfactory receptor neurons,ORNs)可自我更新,成年人的嗅上皮也仍保持神经再生和分化能力,而嗅上皮的这种特性使嗅觉障碍的恢复和治疗成为可能.ORNs是脊椎动物中惟一一种胞体同外周环境直接接触的神经元.外界环境中细菌、病毒、吸烟以及物理性损伤都可以造成ORNs损伤和死亡.随着对嗅觉及嗅觉障碍等相关研究,在对嗅神经元的增殖与凋亡方面也有更加深入的进展.本文就嗅觉神经元的凋亡与其相关因子的关系进行了综述.
作者 张峻峥 杨一兵 吴锡芳 丛林海
机构地区 [
出处 《国际耳鼻咽喉头颈外科杂志》 2013年第2期-,共4页 International Journal of Otolaryngology-Head and Neck Surgery
关键词 嗅觉受体神经元(Olfactory RECEPTOR Neurons ORNs) 凋亡(Apoptosis) 细胞因子(Cytokines)
分类号 R765 [医药卫生—耳鼻咽喉科]
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参考文献21

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国际耳鼻咽喉头颈外科杂志
2013年 第2期

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