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高胆固醇血症患者踝臂指数与颈动脉粥样硬化的相关性

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摘要 目的探讨高胆固醇血症患者踝臂指数(ABI)与颈动脉粥样硬化(CAS)的相关性。方法选择243例高胆固醇(TC≥5.18 mmol/L)患者,收集相关临床资料,并测量踝臂指数(ABI,<0.9为异常)及颈动脉内膜中层厚度(IMT)。根据IMT分为颈动脉粥样硬化(AS)组135例和非AS组108例,比较两组ABI和ABI降低发生率;将AS组患者根据ABI分为ABI正常组65例和ABI异常组60例,比较两组IMT,分析ABI)与颈动脉粥样硬化(CAS)的相关性。结果 AS组、非AS组ABI分别为0.89±0.66、0.91±0.57,分别有86例(64%)和40例(37%)患者ABI减低,AS组ABI低于非AS组,ABI减低发生率高于非AS组(P均<0.05)。AS组ABI异常者IMT明显高于ABI正常者4(P<0.05)。直线相关性分析显示ABI与IMT呈负相关(r=-0.435,P均<0.05)。结论高胆固醇血症伴颈动脉粥样硬化患者ABI明显减低,ABI与IMT呈负相关。
出处 《山东医药》 CAS 2013年第30期36-37,共2页 Shandong Medical Journal
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