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胰岛β细胞功能受损是2型糖尿病致病的关键因素:遗传学研究进展的启示 被引量:3

Impaired islet β cell function as a critical cause of type 2 diabetes: what could we learn from genetic studies
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摘要 胰岛β细胞功能受损和胰岛素抵抗是2型糖尿病致病的两个关键因素.但是何种因素更为重要尚有争议.
作者 胡仁明 杨震
出处 《中华糖尿病杂志》 CAS 2009年第2期-,共3页 CHINESE JOURNAL OF DIABETES MELLITUS
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参考文献13

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二级参考文献12

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共引文献1

同被引文献40

  • 1Mbanya JC, Pani LN, Mbanya DN, et al. Reduced insulin secretion in offspring of African type 2diabeteic parent. Diabetes Care 2000 ;23 : 1761 - 1765.
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  • 3Doria A, Patti ME, Kahn CR. The emerging genetic archi- tecture of type 2 diabetes. Cell Metab 2008 ;8 : 186 - 200.
  • 4Kulkami RN, Jhala US, Winnay JN, et al. PDX1 haploin sufficiency limits the compensatory islet hyperplasia that occurs in re- sponse to insulin resistance. J Clin Invest 2004;14(6) :828 -836.
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