心肌梗死后β受体阻滞剂,他汀类药物应用情况的调查

Survey of beta-blockers and statins therapy in patients after acute myocardial infarction

【目的】调查急性心肌梗死 (AMI)患者服用 β受体阻滞剂和他汀类降脂药物的现状 ,旨在提高临床医师对 β受体阻滞剂对于AMI早期及其预后的重要意义和他汀类降脂药物对于AMI患者调脂治疗的重要意义。【方法】分析从 2 0 0 0— 2 0 0 2年 2 2 6例因AMI入院的患者出院时服用 β受体阻滞剂、他汀类降脂药物和抗血小板、硝酸酯类药物的情况 ,血清胆固醇水平。【结果】从 2 0 0 0— 2 0 0 2年AMI患者服用 β受体阻滞剂无明显改变 ,使用率较低 ,平均为 37 6 %。他汀类药物的使用情况呈逐年上升的趋势 ,血清胆固醇水平呈逐年下降趋势 ,达标率逐年上升 ,但无统计学意义。【结论】 β受体阻滞剂和他汀类药物对于AMI及其预后具有多种有益效应 ,应加强其应用力度 。

ObjectiveTo survey the use of beta-blockers and statins in the treatment and the long-term secondary preventive methods for acute myocardial infarction (AMI) in order to strengthen the awareness of the clinical significance of beta-blockers and statins.Serum cholesterol level on discharge from hospital and use of beta-blockers and statins were respectively analyzed in 226 patients with AMI admitted to this hospital during 2000 through 2002.Beta-blockers were underused. On the average, only 37.6% of eligible patients received beta-blocker therapy, this rate remained unchanged from 2000 to 2002. The use of statins in the treatment of AMI survivors tended to be increased year by year (48.4%～50.6%) and the percentage of satisfactory control of hypercholesterolemia in AMI survivors also increased year by year (26.1%～34.2%), but they were not statistically significant.[Conclusion]Based on the multiple beneficial effects of beta-blockers and statins on the AMI, it is suggested that underuse of beta-blockers should be improved. The percentage of satisfactory control of hypercholesterolemia should be emphasized.